Complex biology requires new paradigms. Breakthroughs happen when we discover convergences of these complexities and then leverage those insights for therapeutic benefits.
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At GRIK Therapeutics we have elucidated how ion channels gate. There are key endogenous regulators that determine if the channel will open or close and thus conduct ions and alter the electrical behavior.
We use these complex and dynamic mechanisms that nature has devised to alter the opening and closing of ion channels to correct abhorrent cellular behavior arising from disease states. This approach is based on allosteric modulation of phospholipid in the cell membrane that regulate ion channels.
At GRIK Therapeutics we have elucidated how ion channels gate. There are key endogenous regulators that determine if the channel will open or close and thus conduct ions and alter the electrical behavior.
We use these complex and dynamic mechanisms that nature has devised to alter the opening and closing of ion channels to correct abhorrent cellular behavior arising from disease states. This approach is based on allosteric modulation of phospholipid in the cell membrane that regulate ion channels.